文献类型：期刊文献

英文题名：Anchorage-Dependent Living Supramolecular Self-Assembly of Polymeric Micelles

作者：Tang, Zhengmin[1];Gao, Liang[1];Lin, Jiaping[1];Cai, Chunhua[1];Yao, Yuan[1];Guerin, Gerald[1];Tian, Xiaohui[1];Lin, Shaoliang[1]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, Shanghai 200237, Peoples R China

年份：2021

卷号：143

期号：36

起止页码：14684

外文期刊名：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

收录：;EI(收录号：20213810901823);WOS:【SCI-EXPANDED(收录号:WOS:000697286000033)】；

基金：This work was supported by the National Natural Science Foundation of China (51621002, 51833003, 52073095, and 21975073). Support from "the Fundamental Research Funds for the Central Universities" (50321041918013) and projects of Shanghai municipality (20YF1410700, 20ZR1471300) are also appreciated. The authors thank Professor Mitchell A. Winnik and Dr. Shaofei Song for their valuable comments and suggestions.

语种：英文

外文关键词：Supramolecular chemistry - Cell proliferation - Micelles - Anchorages (foundations) - Substrates - Hydrophobicity - Self assembly

摘要：Anchorage-dependent contact-inhibited growth usually refers to on-surface cell proliferation inhibited by the proximity of other cells. This phenomenon, prominent in nature, has yet to be achieved with polymeric micelles. Here, we report the control living supra-macromolecular self-assembly of elongated micelles with a liquid crystalline core onto a hydrophobic substrate via the synergetic interactions between the substrate and aggregates dispersed in solution. In this system, seed formation is a transient phenomenon induced by the adsorption and rearrangement of the core-swollen aggregates. The seeds then trigger the growth of elongated micelles onto the substrate in a living controllable manner until the contact with the substrate is disrupted. Brownian dynamic simulations show that this unique behavior is due to the fusion of the aggregates onto both ends of the anchored seeds. More important, the micelle length can be tuned by varying the substrate hydrophobicity, a key step toward the fabrication of intricate structures.