文献类型：期刊文献

英文题名：Biomimetic Asymmetric Polymer Brush Coatings Bearing Fencelike Conformation Exhibit Superior Protection and Antifouling Performance

作者：Xu, Binbin[1,2];Feng, Chun[1];Lv, Yisheng[2];Lin, Shaoliang[2];Lu, Guolin[1];Huang, Xiaoyu[1]

机构：[1]Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem,Ctr Excellence Mol Synth, Key Lab Synthet & Self Assembly Chem Organ Funct, Shanghai 200032, Peoples R China;[2]East China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2020

卷号：12

期号：1

起止页码：1588

外文期刊名：ACS APPLIED MATERIALS & INTERFACES

收录：;EI(收录号：20200408083880);WOS:【SCI-EXPANDED(收录号:WOS:000507146100162)】；

基金：The authors thank the financial support from National Key Research & Development Program of China (2016YFA0202900), National Science Fund for Distinguished Young Scholars (51825304), National Natural Science Foundation of China (21632009, 51622301, 21674124, 51773222, 51873061, 51873229 and 51961145103), Strategic Priority Research Program of Chinese Academy of Sciences (XDB20000000), Shanghai Scientific and Technological Innovation Project (18JC1410600, 18JC1415500, 18520711900, 18ZR1448600, 19XD1401400, 19YF1410300, 19590750400 and 19DZ1205300), and Innovation Program of Shanghai Municipal Education Commission (2019-01-07-0005-E00012). We are also indebted to Department of Mechanical Engineering, Southeast University (Nanjing, P. R. China) for the SFA measurement.

语种：英文

外文关键词：asymmetric polymer brush; anti-fouling; surface protection; fence-like monolayer; drop coating

摘要：Antifouling surfaces with optimized conformation and compositional heterogeneities are presented with the goal of improving the efficacy of surface protection. The approach exploits the adhesive group (thiol or catechol chain end) to anchor asymmetric polymer brushes (APBs) bearing amphiphilic side chains with synergistic nonfouling and fouling-release abilities onto the surface. The conformation of the APB surface is close to the fencelike structure, which mimics lubricating protein lubricin, endowing the surface with capacity of enhanced protection and antiadhesivity, even facing the high compression of fouling. By utilizing a poly(Br-acrylate-alkyne) macroagent comprising alkynyl and 2-bromopropionate groups, we prepared a series of APB surfaces based on polyacrylate-g-poly(ethylene oxide)/poly(pentafluorophenyl methacrylate) (PA-g-PEO/PPFMA) APBs to explore the influence of the content of the fluorinated segment and bioinspired topological polymer chemistry on their antifouling performance. The APB surfaces can not only provide compositional heterogeneities of PEO and fluorinated segments in each side chain but also give a high surface coverage because of the characteristic of high grafting density of macromolecular brushes. It was found for the first time, as far as we are aware, the fencelike APB surface shows excellent antifouling performance with less protein adsorption (up to 91% off) and cell adhesion (up to 84% off) in comparison with the controlled substrate under relatively long incubation time.