文献类型：期刊文献

英文题名：Highly stereoselective monofluoroolefination: Facile access to (E)-α-fluorinated arylvinyl sulfones from trifluoromethyl α-fluorinated arylsulfonyl gem-diols

作者：Fang, Xiang[1];Zhou, Jun[1];Wang, Wang[1];Yang, Xueyan[1];Wu, Fanhong[2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China

年份：2020

卷号：61

期号：23

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000535721300021)，CCR-EXPANDED(收录号:WOS:000535721300021)】；

基金：The authors thank the National Natural Science Foundation of China (No. 21672151) for financial support.

语种：英文

外文关键词：Monofluoroolefination; Stereoselective; Trifluoromethyl alpha-fluorinated arylsulfonyl gem-diols; alpha-Fluorinated arylvinyl sulfones

摘要：An excellent stereoselective direct synthesis of trisubstituted (E)-alpha-fluorinated arylvinyl sulfones employing trifluoromethyl alpha-fluorinated arylsulfonyl gem-diols and aryl aldehydes under mild reaction conditions has been developed, which affords alpha-fluorinated arylvinyl sulfones in high yields with E-isomer only. The desired products can be further transformed into more useful fluoroolefins through debenzenesulfonyl process. (C) 2020 Elsevier Ltd. All rights reserved.