文献类型：期刊文献

英文题名：Direct Reductive Amination from Ketones, Aldehydes to Synthesize Amines Using N, S-Dual Doped Co/C Catalyst

作者：Zhang, Hongwei[1];Liu, Ying[1];Zhang, Ling[2];Wang, Xiong[1];Sun, He[2];Liu, Chengyu[2];Ye, Jinxing[3];Cheng, Ruihua[1,3]

机构：[1]East China Univ Sci & Technol, Sch Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Sch Pharm, Shanghai 200237, Peoples R China;[3]Guangdong Univ Technol, Sch Biomed & Pharmaceut Sci, Guangzhou 510006, Peoples R China

年份：2022

卷号：152

期号：12

起止页码：3586

外文期刊名：CATALYSIS LETTERS

收录：;EI(收录号：20220711614497);WOS:【SCI-EXPANDED(收录号:WOS:000751237600002)，CCR-EXPANDED(收录号:WOS:000751237600002)】；

基金：This work was partially sponsored by the National Natural Science Foundation of China (22071056).

语种：英文

外文关键词：Heterogeneous catalysis; Hydroamination; Supported catalysts; Ketones; Reductive amination

摘要：As a key intermediate in natural products and pharmaceutics, N-(R, R)-phenethyl-1-indane was directly prepared by one-pot reductive amination of 1-indanone and R-(+)-alpha-phenethylamine using abundant molecular hydrogen as a reductant. Compared with the traditional noble metal catalyst, the Co-VB1(1:2)/C-900 catalysts showed higher selectivity in this reaction, and generated the N-(R, R)-phenethyl-1-indane with high yield. The Co-VB1(1:2)/C-900 catalysts were prepared by the modification of thiamine hydrochloride (VB1) as nitrogen and sulfur sources. At the same time, the catalyst was reusable for several times. The synthesis of N-(R, R)-phenethyl-1-indane was cost-effective and atom-economical. The catalyst also presented moderate to good catalytic activities in reductive amination for a series substrate, ranging from aldehydes or ketones, to giving access to various valuable compounds. [GRAPHICS] .