文献类型：期刊文献

英文题名：Red-light-excited dynamic near-infrared organic afterglow materials for in vivo bioimaging

作者：Zhou, Lei[1,2];Yang, Jiacheng[1,2];He, Zhenyi[1,2];Wu, Zhiqin[1,2];Jiang, Ping[1,2];Song, Jinming[1,2];Ma, Liangwei[1,2];Tian, He[1,2];Ma, Xiang[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Meilong Rd 130, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Inst Fine Chem,Sch Chem & Mol Engn, Meilong Rd 130, Shanghai 200237, Peoples R China

年份：2026

卷号：15

期号：1

外文期刊名：LIGHT-SCIENCE & APPLICATIONS

收录：;EI(收录号：20262420888032);WOS:【SCI-EXPANDED(收录号:WOS:001789042100002)】；

基金：We gratefully acknowledge the financial support from the National Natural Science Foundation of China (22125803, T2488302, 22305080), the Science and Technology Commission of Shanghai Municipality (24DX1400200), the Guangxi Department of Science and Technology (AA23062016), the Fundamental Research Funds for the Central Universities, and the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM404).

语种：英文

外文关键词：Bioimaging - Doping (additives) - Energy gap

摘要：Extending the excitation and emission wavelengths into the red or even near-infrared region is a highly challenging yet scientifically valuable research topic in the field of organic afterglow materials. To solve this issue, we put forward a twisted intramolecular charge transfer dopant molecule design strategy, in which long-lived electron-deficient dopant is decorated with electron-rich substituent. In this way, the orbital energy level of the dopant can be lowered while maintaining the compatibility with the host. Benefiting from the twisted molecular conformation and small energy gap, the obtained dopant (CN) shows visible-light-excited afterglow with various performance (decay path, lifetime, emission wavelength) when doped into different matrices. Particularly, the maximum excitation wavelength extends to 567 nm and tails to 700 nm when CN is doped into benzophenone matrix. More importantly, the maximum emission wavelength of the afterglow extends to 725 nm (tau = 67.82 ms). We also successfully apply this material in autofluorescence-free bioimaging. This work provides a viable molecular design strategy for developing red-light-excitable near-infrared afterglow materials and demonstrates their potential for in vivo bioimaging.