文献类型：期刊文献

中文题名：Copper（I）-Catalyzed Trifluoromethylation of Phthalic Anhydride Derivatives with （Trifluoromethyl）trimethylsilane

英文题名：Copper（I）-Catalyzed Trifluoromethylation of Phthalic Anhydride Derivatives with （Trifluoromethyl）trimethylsilane

作者：Mingxi Wu[1];Mingjin Wang[1];Song Cao[1,2]

机构：[1]Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China;[2]Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

年份：2013

卷号：31

期号：7

起止页码：945

中文期刊名：Chinese Journal of Chemistry

外文期刊名：中国化学（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2013_2014】；

基金：Acknowledgement We are grateful for financial supports from the National Natural Science Foundation of China （Nos. 21072057, 21272070）, the 973 Program （No. 2010CB126101）, the Key Project in the National Science ＆ Technology Pillar Program of China in the twelfth five-year plan period （No. 2011BAE06B05）.

语种：英文

中文关键词：trifluoromethylation;copper（l）-catalyzed;phthalic anhydrides;（trifluoromethyl）trimethylsilane

外文关键词：trifluoromethylation, copper（l）-catalyzed, phthalic anhydrides, （trifluoromethyl）trimethylsilane

摘要：An efficient copper-catalyzed trifluoromethylation of substituted phthalic anhydrides using （trifluoromethyl） trimethylsilane （Me3SiCF3） as a nucleophilic trifluoromethylating reagent in the presence of 1,10-phenanthroline and KF, followed by quenching the reaction mixture with water has been developed. A possible mechanism was suggested.
An efficient copper-catalyzed trifluoromethylation of substituted phthalic anhydrides using （trifluoromethyl） trimethylsilane （Me3SiCF3） as a nucleophilic trifluoromethylating reagent in the presence of 1,10-phenanthroline and KF, followed by quenching the reaction mixture with water has been developed. A possible mechanism was suggested.