文献类型：期刊文献

英文题名：Electrocatalytic Efficiency Analysis of Catechol Molecules for NADH Oxidation during Nanoparticle Collision

作者：Zhao, Li-Jun;Qian, Ruo-Can;Ma, Wei;Tian, He;Long, Yi-Tao[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Sch Chem & Mol Engn, Dept Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2016

卷号：88

期号：17

起止页码：8375

外文期刊名：ANALYTICAL CHEMISTRY

收录：;EI(收录号：20163702788259);WOS:【SCI-EXPANDED(收录号:WOS:000382805900007)】；

基金：This research was supported by the National Natural Science Foundation of China (Nos. 21327807 and 21421004), the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning (No. YJ0130504), the Program of Shanghai Subject Chief Scientist (No. 15XD1501200), and the Programme of Introducing Talents of Discipline to Universities (No. B16017).

语种：英文

外文关键词：Microelectrodes - Gold nanoparticles - Oxidation - Phenols - Carbon fibers - Electrocatalysis

摘要：Electrocatalysis of molecules is a hot research topic in biological and energy-related chemistry. Here, we develop a new system to study the electrocatalytic efficiency of a single catechol molecule for NADH oxidation by single functionalized nanoparticle collision at ultramicroelectrodes (UMEs). The proposed system is composed of gold nanoparticles (AuNPs) functionalized with catechol molecules and a carbon-fiber ultramicroelectrode. In the absence of NADH, when a functionalized AuNP collides with an UME at a suitable voltage, a small current spike is generated due to the oxidation of catechol molecules modified on the surface of AuNP. In the presence of NADH, the current spike is significantly amplified by the combined effects of the oxidation and electrocatalysis for NADH of catechol molecules. By analyzing the variations of the average peak charges and durations without or with NADH, we calculate that around five thousands NADH molecules could be catalyzed per second by a single catechol molecule, suggesting the successful establishment of this novel catalytic system. Thus, the proposed strategy could be used as a promising platform for research of other molecular electrocatalytic systems.