文献类型：期刊文献

中文题名：基于有限元计算的微流控聚焦装置液滴生成特性分析

英文题名：Analysis of Droplet Generation Characteristics of Microfluidic Focusing Device Based on Finite Element Calculation

作者：乔督[1];李红霞[1];赵丹阳[1];王敏杰[1];任福正[2]

机构：[1]大连理工大学机械工程学院,大连116024;[2]华东理工大学药学院,上海200237

年份：2022

卷号：43

期号：7

起止页码：1886

中文期刊名：工程热物理学报

外文期刊名：Journal of Engineering Thermophysics

收录：CSTPCD;;EI(收录号：20222912386726);Scopus;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

基金：国家自然科学基金(No.11502044);中央高校基本科研业务费项目(No.DUT17RC(3)104)。

语种：中文

中文关键词：微流控;聚焦装置;液滴生成;流场分析

外文关键词：microfluidic;focusing device;droplet generation;flow field analysis

摘要：研究微流控聚焦装置液滴生成特性是液滴微流控芯片结构优化设计的基础。利用水平集方法结合有限元技术建立了微流控聚焦装置内液滴生成过程的数值计算模型,并分析了分散相与连续相流速比、微流道几何结构对液滴生成机制和液滴生成特性的影响规律。在一定的流速比、微流道入口宽度比范围内,均生成了性态良好的液滴。当分散相与连续相入口宽度比大于1时,液滴尺寸随连续相入口宽度、连续相流速的增大而减小,液滴生成频率随连续相入口宽度、连续相流速的增大而增大;当分散相与连续相入口宽度比小于1时,液滴尺寸随分散相入口宽度增大而增大,随连续相流速的增大而减小,液滴生成频率随分散相入口宽度、连续相流速的增大而增大。数值计算结果表明:微流控聚焦装置液滴生成受几何结构、流速及两相流体物性参数的耦合作用,模拟计算的结果可为微流控聚焦装置结构优化设计提供指导。
Studying the droplet generation characteristics of the microfluidic focusing device is the basis of the structural optimization design of the droplet microfluidic chip.The numerical calculation model of the droplet generation process in the microfluidic focusing device was established by using the level set method and the finite element technology.The influence of the flow rate ratio of the dispersed phase to the continuous phase and the geometry of the microchannel on the droplet generation mechanism and droplet generation characteristics are analyzed.Within a certain range of flow rate ratio and microchannel inlet width ratio,acceptable droplets were generated.When the ratio of the inlet width of the dispersed phase to the continuous phase is greater than 1,the droplet size decreases with the increase of the continuous phase inlet width and the continuous phase flow rate,and the droplet generation frequency increases with the increase of the continuous phase inlet width and the continuous phase flow rate;when the ratio of the inlet width of the dispersed phase to the continuous phase is less than 1,the droplet size increases with the increase of the dispersed phase inlet width,and decreases with the increase of the continuous phase flow rate.The droplet generation frequency increases with the increase of the inlet width of the dispersed phase and the flow rate of the continuous phase.Numerical calculation results show that the droplet generation of the microfluidic focusing device is coupled by the geometric structure,flow rate and physical parameters of the two-phase fluid.The simulation results can provide guidance for the structural optimization design of the microfluidic focusing device.