文献类型：期刊文献

英文题名：An enzyme-free capacitive glucose sensor based on dual-network glucose-responsive hydrogel and coplanar electrode

作者：Cai, Yingjie[1];Yang, Dasheng[1];Yin, Ruixue[1];Gao, Yang[1];Zhang, Hongbo[1];Zhang, Wenjun[2]

机构：[1]East China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai, Peoples R China;[2]Univ Saskatchewan, Div Biomed Engn, Saskatoon, SK, Canada

年份：2021

卷号：146

期号：1

起止页码：213

外文期刊名：ANALYST

收录：;EI(收录号：20210309770473);WOS:【SCI-EXPANDED(收录号:WOS:000607369300014)】；

基金：The authors would like to gratefully acknowledge the financial support by the Shanghai Science and Technology Innovation Program (No. 19441909600), the Opening project of Shanghai Key Laboratory of Orthopedic Implant (KFKT2019001) and the National Natural Science Foundation of China (Grant No. 51705154).

语种：英文

外文关键词：Electrodes - Glucose - Glucose oxidase - Hydrogels - Curing - Dielectric properties - Costs - Capacitive sensors

摘要：Glucose sensors are vital devices for blood glucose detection in the diabetes care. Different from traditional electrochemical devices based on glucose oxidase, the glucose sensor based on the glucose-responsive hydrogel is more robust owing to its enzyme-free principle. However, integrating the high sensitivity, fast response, wide measuring range and low-cost fabrication into a hydrogel sensor is still challenging. In this study, we present a physical capacitive sensor, which consists of interdigital carbon electrodes (ICEs) fabricated by a direct laser writing technology and glucose-responsive hydrogel (DexG-Con A hydrogel) built by UV curing in situ. The dielectric property of DexG-Con A hydrogel changes accordingly with the change in environmental glucose concentration. Experimental results demonstrate that in a glucose concentration range of 0-30 mM, the proposed hydrogel sensor is capable of measuring the glucose level in a repeatable and reversible manner, showing a short responsive time of less than 2 min and a high sensitivity of 8.81 pF mM(-1) at a glucose range of 0-6 mM. Owing to its simple fabrication process, low-cost and high performance, the proposed glucose sensor shows great potential on batch production for continuous glucose monitoring application.