文献类型：期刊文献

英文题名：pH-activated polymeric profragrances for dual-controllable perfume release

作者：Liu, Ming[1,2];Yan, Chenxu[1,2];Han, Jianwei[1,2];Guo, Zhiqian[1,2];Zhu, Wei-Hong[1,2];Xiao, Zuobing[3];Wu, Yue[4];Huang, Jian[4]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Sch Chem & Mol Engn,Frontiers Sci Ctr Mat & Dynam, Key Lab Adv Mat,Feringa Nobel Prize Scientist Joi, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem,Joint Int Res Lab Precis Chem & Mo, Sch Chem & Mol Engn,Frontiers Sci Ctr Mat & Dynam, Key Lab Adv Mat,Feringa Nobel Prize Scientist Joi, Shanghai 200237, Peoples R China;[3]Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai, Peoples R China;[4]Apple Flavor & Fragrance Grp Co Ltd, Shanghai, Peoples R China

年份：2021

卷号：67

期号：8

外文期刊名：AICHE JOURNAL

收录：;EI(收录号：20211910329653);WOS:【SCI-EXPANDED(收录号:WOS:000644879500001)】；

基金：This work was supported by National Key Research and Development Program (2016YFA0200300), NSFC Science Center Program (21788102) and Creative Research Groups (21421004), NSFC/China (21636002 and 21622602), Shanghai Municipal Science and Technology Major Project (2018SHZDZX03), and Program of Introducing Talents of Discipline to Universities (B16017).

语种：英文

外文关键词：dual‐ controllability; nanoprofragrances; perfume release; pH‐ activated polymer

摘要：Design of controllable nanoprofragrances is critically challenging in cosmetic and decoration industries. Given that most profragrances based on physical encapsulation always suffer unreliable controllability, undefined loading efficiency, and poor stability, here we have for the first time constructed dual-controllable profragrance platform based on pH-activated polymer to achieve the specific pH-triggered fragrance release, which consists of hydrophilic PEG unit, hydrophobic pH-activated unit, and pH-triggered unit, thereby guaranteeing profragrances with delicate controllability, homogeneous nanoparticles, well-defined loading efficiency, and high stability. Dynamic laser scattering experiments demonstrate that the activated polymers possess excellent pH-switchable property with high stability. Particularly, time-dependent headspace release performance of all three profragrances is fitting to First-Order kinetic model (R-2 > 0.99). Finally, the step-by-step controllability of the profragrance platform with pH-activated behavior and subsequently pH-triggered release is realized both in aqueous solution and on targeted leather surface, which is highly desirable for the long-lasting scent.