文献类型：期刊文献

英文题名：Functional connectivity between prefrontal cortex and striatum estimated by phase locking value

作者：Zhang, Yan[1];Pan, Xiaochuan[1];Wang, Rubin[1];Sakagami, Masamichi[2]

机构：[1]E China Univ Sci & Technol, Inst Cognit Neurodynam, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Tamagawa Univ, Brain Sci Inst, Tamagawagakuen 6-1-1, Machida, Tokyo 1948610, Japan

年份：2016

卷号：10

期号：3

起止页码：245

外文期刊名：COGNITIVE NEURODYNAMICS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000376263700006)】；

基金：This work is supported by National Nature Science Foundation of China (Nos. 11232005, 11472104), and sponsored by Shanghai Pujiang Program (No. 13PJ1402000).

语种：英文

外文关键词：Prefrontal cortex; Striatum; Phase-locking value; Beta band; Gamma band

摘要：The interplay between the prefrontal cortex (PFC) and striatum has an important role in cognitive processes. To investigate interactive functions between the two areas in reward processing, we recorded local field potentials (LFPs) simultaneously from the two areas of two monkeys performing a reward prediction task (large reward vs small reward). The power of the LFPs was calculated in three frequency bands: the beta band (15-29 Hz), the low gamma band (30-49 Hz), and the high gamma band (50-100 Hz). We found that both the PFC and striatum encoded the reward information in the beta band. The reward information was also found in the high gamma band in the PFC, not in the striatum. We further calculated the phase-locking value (PLV) between two LFP signals to measure the phase synchrony between the PFC and striatum. It was found that significant differences occurred between PLVs in different task periods and in different frequency bands. The PLVs in small reward condition were significant higher than that in large reward condition in the beta band. In contrast, the PLVs in the high gamma band were stronger in large reward trials than in small trials. These results suggested that the functional connectivity between the PFC and striatum depended on the task periods and reward conditions. The beta synchrony between the PFC and striatum may regulate behavioral outputs of the monkeys in the small reward condition.