文献类型：期刊文献

英文题名：A Versatile Strategy to Main Chain Sulfur/Selenium-Functionalized Polycarbonates by Macro-Ring Closure of Diols and Subsequent Ring-Opening Polymerization

作者：Wei, Chao[1];Zhang, Yan[1];Yan, Bingkun[1];Du, Zhengzhen[1];Lang, Meidong[1]

机构：[1]East China Univ Sci & Technol, Sch Mat & Sci & Engn, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China

年份：2018

卷号：24

期号：4

起止页码：789

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20175204589976);WOS:【SCI-EXPANDED(收录号:WOS:000425822100006)】；

基金：Financial support from the National Key Research and Development Program ( 2016YFC1100700), Shanghai Natural Science Foundation ( 17ZR1407100) are gratefully acknowledged.

语种：英文

外文关键词：catalysis; enzymes; ring opening polymerization; selenium; sulfur

摘要：Herein, a new class of main chain functionalized aliphatic polycarbonates with sulfur/selenium functional groups on the backbone is reported. Sulfur/selenium-containing cyclic carbonate monomers (M-R) are designed and synthesized by enzyme-catalyzed intermolecular macroring closure of related diols. The proposed synthetic strategy is tolerant of other functionalities such as N-substituted groups. The ring opening polymerization (ROP) of M-R occurs readily as a versatile route to generate a new family of main chain sulfur/selenium substituted aliphatic polycarbonates (PR) with predictable molecular weights (MW), narrow molecular-weight distribution and controlled copolymer composition. The resultant polymers can be oxidized and/or reduced by treatment with hydrogen peroxide (H2O2) or dithiothreitol (DTT), highlighting their potential for applications in the stimuli-responsive field and inflammation/cancer targeting. With these desirable results, it is revealed that this versatile technique can provide a broad-reaching method to the next generation of innovative materials, especially, well-defined biodegradable chalcogen-based main chain functional biomaterials.