文献类型：期刊文献

英文题名：A facile, catalyst- and additive-free, and scalable approach to the photochemical preparation of disulfides from organosulfenyl chlorides

作者：Liu, Wei[1,2];Wang, Jiayi[1];Song, Gonghua[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]State Key Lab Fluorine Containing Funct Membrane M, Zibo 256400, Shandong, Peoples R China

年份：2024

卷号：14

期号：44

起止页码：32200

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20244217226867);WOS:【SCI-EXPANDED(收录号:WOS:001329964100001)】；

语种：英文

外文关键词：Free radical reactions - Reaction kinetics

摘要：A novel, clean and efficient protocol for the preparation of disulfides has been developed through the photochemical radical homo- and cross-coupling reaction of sulfenyl chlorides under LED irradiation and without the use of any catalyst and additive. The representative photochemical homo-coupling of trichloromethyl sulfenyl chloride has been successfully conducted on kilogram-scale in a continuous flow mode. The solvent and the main byproduct can be recovered in high yields, which makes the approach be highly atom economical. Various disulfides were prepared by the homo- and cross-coupling of sulfenyl chlorides under LED irradiation without the use of any catalyst or additive. The representative reaction was performed on kilogram-scale in a continuous flow mode.