文献类型：期刊文献

英文题名：Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans

作者：Jiang, Shanshan[1];Hu, Bin[1];Yu, Xingxin[1];Deng, Weiping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2014

卷号：32

期号：8

起止页码：694

外文期刊名：CHINESE JOURNAL OF CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000341236900008)，CCR-EXPANDED(收录号:WOS:000341236900008)】；

语种：英文

外文关键词：Michael addition-Lactonization; dihydrobenzofuran; Fc-PIP

摘要：A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst (Fc-PIP) was developed, furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities (94%-98% ee) and good diastereoselectivities (up to 99/1).