文献类型：期刊文献

英文题名：Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

作者：Li, Yongsheng[1];Shao, Andong[2,3];Wang, Yao[1];Mei, Ju[2,3];Niu, Dechao[1];Gu, Jinlou[1];Shi, Ping[4];Zhu, Weihong[2,3];Tian, He[2,3];Shi, Jianlin[5]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Lab Low Dimens Mat Chem,Minist Educ, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[4]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[5]Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China

年份：2016

卷号：28

期号：16

起止页码：3187

外文期刊名：ADVANCED MATERIALS

收录：;EI(收录号：20161002053249);WOS:【SCI-EXPANDED(收录号:WOS:000374577400019)】；

基金：Y.L., A.S., and Y.W. contributed equally to this work. This work was supported by National 973 Program (2012CB933602, 2013CB733700), NSFC/China, NSFC for Creative Research Groups (21421004) and Distinguished Young Scholars (21325625), 111 project (B14018), Oriental Scholarship, Shanghai Pujiang Program (13PJD010) and Fundamental Research Funds for the Central Universities. All animal experiments were performed in compliance with the Guidelines for the Care and Use of Research Animals established by the East China University of Science and Technology Animal Studies Committee.

语种：英文

外文关键词：Tumors - Nanospheres - Biocompatibility - Morphology

摘要：Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsulating QM-2 (quinoline-malononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of approximate to 30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.