详细信息

An efficient enantioselective method for asymmetiric Michael addition of nitroalkanes to α,β-unsaturated aldehydes  ( SCI-EXPANDED收录)  

文献类型:期刊文献

英文题名:An efficient enantioselective method for asymmetiric Michael addition of nitroalkanes to α,β-unsaturated aldehydes

作者:Wang, Yongcan[3];Li, Pengfei[3];Liang, Xinmiao[1,3];Zhang, Tony Y.[2];Ye, Jinxing[1,3]

机构:[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Eli Lilly & Co, Indianapolis, IN 46285 USA;[3]Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

年份:2008

期号:10

起止页码:1232

外文期刊名:CHEMICAL COMMUNICATIONS

收录:;WOS:【SCI-EXPANDED(收录号:WOS:000254579500023),CCR-EXPANDED(收录号:WOS:000254579500023)】;

语种:英文

摘要:The addition of nitroalkanes to alpha,beta-unsaturated aldehydes under the catalysis of (S)-2-(dipheny](trimethylsilyloxy)methyl)pyrrolidine and lithium acetate as additive afforded gamma-nitroaldehydes in good yield and up to 97% ee.

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