文献类型：期刊文献

中文题名：卵磷脂类液晶乳液的性能

英文题名：Properties of Lecithin Liquid Crystal Emulsion

作者：周梦[1];舒鹏[2];冯蓓[3];尚亚卓[1];刘洪来[1];李成亮[3]

机构：[1]华东理工大学化学与分子工程学院,结构可控先进功能材料及其制备教育部重点实验室,上海200237;[2]无限极(中国)有限公司,广州510663;[3]莱博药妆技术(上海)股份有限公司,上海200233

年份：2018

卷号：35

期号：10

起止页码：1227

中文期刊名：应用化学

外文期刊名：Chinese Journal of Applied Chemistry

收录：CSTPCD;;北大核心:【北大核心2017】；CSCD:【CSCD2017_2018】；

基金：国家自然科学基金资助项目(21476072)；“中央高校基本科研业务费专项资金”资助。

语种：中文

中文关键词：卵磷脂类乳化剂;层状液晶;乳液性能;护肤乳液

外文关键词：lecithin emulsifier;lamellar liquid crystals;emulsion properties;skin care emulsions

摘要：以卵磷脂为主乳化剂制备了一款液晶乳液。该乳液在皮肤上具有良好的稳定性能,在皮肤表层停留6 h仍能保持完整的液晶结构,克服了一般液晶乳液中液晶织构无法在皮肤上长时间停留的问题。液晶结构在皮肤温度范围内具有较高的稳定性,可为液晶乳液其他性能的发挥提供条件。基于此,我们采用体外称重法研究了液晶乳液的锁水性,发现液晶乳液锁水性能明显优于传统乳液,实验7 h后仍能保持原有水分总质量的50%;体外透析实验证实,液晶乳液表现出显著的缓释性能且能释放完全,7 h后目标分子(水杨酸钠)释放率可达96%;耐温性能研究表明,液晶乳液耐高温性能及低温冻融性能优良,且温度对乳液中层状液晶的影响是可恢复的;采用离心法、高低温循环和高低温长时间(3个月)放置的方法探究了乳液储运稳定性,结果表明,液晶乳液产品储运稳定性极佳,便于实际的应用和储运。该研究不仅可为开发多效的高端化妆品提供必要信息和参考数据,而且有望拓展卵磷脂类液晶乳化剂体系的应用范畴。
A kind of liquid crystal emulsion was prepared with lecithin as the main emulsifier.The emulsion has good stability on the skin.The whole liquid crystal structure can be maintained for 6 hours on the surface of skin.It overcomes the problem that liquid crystal texture cannot stay on the skin for a long time in general liquid crystal emulsion.Liquid crystal structure has a high stability near skin temperature.It can provide conditions for other performances of liquid crystal emulsion.The water locking properties of different emulsions are measured by in vitro weighing method and the water locking property of liquid crystal emulsion is better than that of traditional emulsion.There are still fifty percent of the total water contents after 7 h.The results of dialysis experiments in vitro confirm that the liquid crystal emulsion has a remarkable slow-release property and can be released completely.The release ratio of target molecule is up to 96%after 7 h.It also shows that liquid crystal emulsion has excellent temperature resistance and low temperature freeze-thaw properties.The effect of temperature on the lamellar liquid crystals in emulsion is recoverable.The storage and transportation stability of emulsion is studied by the centrifugal method,high and low temperature cycle and placement under high and low temperature for 3 months.It shows that liquid crystal emulsion products have excellent storage and transportation stability.It is convenient for practical application and storage and transportation.The study not only provides necessary information and reference data for the development of multi-effect upmarket cosmetics,but also expands the application category of lecithin liquid crystal emulsifier system.