文献类型：期刊文献

英文题名：Modulating the selectivity by switching sensing media: A bifunctional chemosensor selectivity for Cd2+ and Pb2+ in different aqueous solutions

作者：Xu, Lin[1]; Xu, Yufang[1]; Zhu, Weiping[1]; Sun, Xiaolong[1]; Xu, Zheng[1]; Qian, Xuhong[1]

机构：[1] Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

年份：2012

卷号：2

期号：15

起止页码：6323

外文期刊名：RSC Advances

收录：EI(收录号：20123015270410)

语种：英文

外文关键词：Solutions - Chemosensor - Fluorescence imaging - Colorimetry - Metals - Physiology

摘要：A novel bifunctional fluorescent probe RI, based on rhodamine with isatin, was designed and synthesized. Switching of the selectivity of RI between various metal ions was achieved by judicious choice of sensing media. RI gives a turn-on fluorometric and colorimetric signal toward Cd2+ in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) (10 mM, CH 3OH-H2O, 4:6, v/v, pH 7.6) buffer solution and a turn-on colorimetric signal toward Pb2+ in Tris-HCl (70 mM, CH 3OH-H2O, 6:4, v/v, pH 7.6) buffer solution. To the best of our knowledge, this is the first example of a chemosensor based on a small molecule that can selectively recognize both Cd2+ and Pb2+ in different sensing systems. Fluorescence imaging of Cd2+ in living cells was also obtained. ? 2012 The Royal Society of Chemistry.