文献类型：期刊文献

英文题名：Ultrasensitive fluorescence polarization DNA detection by target assisted exonuclease III-catalyzed signal amplification

作者：Zhang, Min[1];Guan, Yi-Meng[1];Ye, Bang-Ce[1]

机构：[1]E China Univ Sci & Technol, Lab Biosyst & Microanal, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2011

卷号：47

期号：12

起止页码：3478

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000288085600040)】；

基金：This work was financially supported by NSF21075040, the Shanghai 09JC1404100, 863 project (2007AA02Z331), NCET-07-0287, SKLBE Fund 2060204, and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：Single stranded DNA sequences can be detected by target assisted exonuclease III-catalyzed signal amplification fluorescence polarization (TAECA-FP). The method offers an impressive detection limit of 83 aM within one hour for DNA detection and exhibits high discrimination ability even against a single base mismatch.