文献类型：期刊文献

英文题名：Synthesis and Characterization of Ciprofloxacin Pendant Antibacterial Cationic Polymers

作者：Xue, Y.[1,2];Guan, Y.[2];Zheng, A.[2];Wang, H.[1];Xiao, H.[1]

机构：[1]Univ New Brunswick, Dept Chem Engn, Fredericton, NB E3B 5A3, Canada;[2]E China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, Key Lab Ultrafine Mat,Minist Educ, Shanghai 200237, Peoples R China

年份：2012

卷号：23

期号：8

起止页码：1115

外文期刊名：JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

收录：;EI(收录号：20121214867573);WOS:【SCI-EXPANDED(收录号:WOS:000302457200009)】；

基金：This study was financially supported by the Scientific Research Foundation of State Education Ministry in the form of the Returned Overseas Chinese Scholars, NSERC Sentinel Network (Canada), Shanghai Leading Academic Discipline Project (B502) and Shanghai Key Laboratory Project (08DZ2230500).

语种：英文

外文关键词：Ciprofloxacin; fluoroquinolone; antimicrobial polymers; acrylamide

摘要：A methacrylate monomer containing ciprofloxacin (CPF) was synthesized, followed by the free-radical co-polymerization of the methacrylate monomer, acrylamide and diallyl dimethyl ammonium chloride (DADMAC). The resulting antimicrobial cationic tripolymers were characterized by H-1-NMR, gel-permeation chromatography, thermogravimetric analysis and differential scanning calorimetry. The in vitro antibacterial activity of the monomer, as well as of the polymers, was investigated against E. coli. The CPF pendant tripolymer exhibited excellent antibacterial activities, thus permitting the cationic tripolymers to be used as antibacterial intensifier, retention or filtration aid for various hygiene products, including those based on cellulose fibres. (C) Koninklijke Brill NV, Leiden, 2012