文献类型：期刊文献

英文题名：Enzymatic synthesis of ethyl glucoside lactate in non-aqueous system

作者：Wei, Dong-Zhi[1,2]; Zou, Ping[1,2]; Tu, Mao-Bing[1]; Zheng, Hong[2]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Biochem, Shanghai 200237, Peoples R China

年份：2002

卷号：18

期号：4-6

起止页码：273

外文期刊名：JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

收录：;EI(收录号：2002477218146);WOS:【SCI-EXPANDED(收录号:WOS:000178982300011)】；

语种：英文

外文关键词：ethyl glucoside; alpha-hydroxy acid; lipase; transesterification; conversion

摘要：Ethyl glucoside lactate, a novel alpha-hydroxy acid derivative, was synthesized by transesterification in non-aqueous phase using immobilized lipase as biocatalyst. Parameters such as solvent type, substrate concentration, reaction temperature, and enzyme concentration were investigated to optimize the lipase-catalyzed transesterification. In solvent-free system with butyl lactate as both acyl donor and solvent, a 71% conversion was achieved. In order to investigate the effect of initial water content, the reactions were carried out in the mediums treated with molecular sieves. The results showed that conversion and initial rate decreased with the increase of water content. The conversion and initial rate reached to 95% and 67.4 mM/h, respectively, by carrying out the reaction under reduced pressure, which was employed to eliminate butanol and the initial water. (C) 2002 Published by Elsevier Science B.V.