文献类型：期刊文献

英文题名：Phenylboronic acid derivative-modified (6,5) single-wall carbon nanotube probes for detecting glucose and hydrogen peroxide

作者：Qiao, Yunfan[1];Zhao, Rushi[2];Zhang, Min[2];Zhang, Hongyang[1];Wang, Yuerong[1];Hu, Ping[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China

年份：2019

卷号：9

期号：4

起止页码：2258

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20190406417642);WOS:【SCI-EXPANDED(收录号:WOS:000457783900057)】；

基金：We thank Dr Geyou Ao for her critical comments on the manuscript. This research was financially supported by the National Natural Science Foundation of China (No. 81573397) and Shanghai Natural Science Foundation (No. 15ZR1409400).

语种：英文

外文关键词：Probes - Single-walled carbon nanotubes (SWCN) - Infrared devices - Purification - Fluorescence - Glucose - Organic acids - Oxidation - Yarn

摘要：In this paper, we presented a new method for constructing near-infrared fluorescence probes and their applications in detecting glucose and hydrogen peroxide (H2O2). We used purified (6,5) single-wall carbon nanotubes (SWCNTs) separated by a polyethylene glycol/dextran aqueous two-phase system as the basis for near-infrared probes. Different phenylboronic acids were used for non-covalent modification of SWCNTs (6,5). Glucose was detected by the specific binding of the boronic acid group with cis-diol. Hydrogen peroxide was detected by horseradish peroxidase (HRP) combined with phenylboronic-acid-modified SWCNTs. The results revealed that the fluorescence intensity of purified SWCNTs was significantly enhanced without other chiral nanotube interactions compared to that of the raw SWCNT material. The fluorescence responses of 3-carboxy-5-nitrophenylboronic acid-modified purified CNTs could be used to effectively measure glucose in the concentration range from 0.01 mu M to 0.50 mu M with an interval linear index of R-2 = 0.996 (LOD = 1.7 mu M, S/N = 3). The detected H2O2 with the 3-aminobenzeneboronic acid-modified (6,5) SWCNT with HRP was in the concentration range from 5.0 mu M to 40 mu M with an interval linear index of R2 = 0.997 (LOD = 0.85 mu M, S/N = 3). Moreover, this sensor exhibited a strong anti-interference effect without biological matrix fluorescence effects above 1000 nm wavelength. Thus, the proposed novel near-infrared fluorescence probes employed for reducing the interference of the biomatrix in this region are expected to be used in subsequent biosensor investigations.