文献类型：期刊文献

英文题名：Resonance scattering particles as biological nanosensors in vitro and in vivo

作者：Li, Yang;Jing, Chao;Zhang, Lei;Long, Yi-Tao[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

年份：2012

卷号：41

期号：2

起止页码：632

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000298854900009)】；

基金：This work was supported by Major Research Plan of National Natural Science Foundation of China (91027035), Key Program of National Natural Science of China (20933007) and the Fundamental Research Funds for the Central Universities (Grant No. WK1013002). We especially thank Dr Andrew M. Smith in Emory University for critical and fruitful discussion and comments on the manuscript. Y.T.L. is supported by the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning.

语种：英文

摘要：Recently dark-field microscopy and Rayleigh scattering spectroscopy have emerged as complementary technologies for ultrasensitive biological detection and imaging with high spatial and temporal resolution. Plasmonic resonant nanoparticles are key nano-scale probes for these technologies that have enabled single-molecule sensitivity and imaging. In this tutorial review, we focus on the use of plasmonic probes as single-particle biological nanosensors in vitro and in vivo. The progress in this field over the last decade will be highlighted.