文献类型：期刊文献

英文题名：Palladium-Catalyzed Room-Temperature Acylative Suzuki Coupling of High-Order Aryl Borons with Carboxylic Acids

作者：Si, Shufen[1];Wang, Chen[1];Zhang, Nan[1];Zou, Gang[1]

机构：[1]E China Univ Sci & Technol, Dept Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2016

卷号：81

期号：10

起止页码：4364

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20162302460051);WOS:【SCI-EXPANDED(收录号:WOS:000376476400044)，CCR-EXPANDED(收录号:WOS:000376476400044)】；

基金：We are grateful for financial support provided by the National Natural Science Foundation of China (21472041).

语种：英文

外文关键词：Ketones - Cost effectiveness - Palladium

摘要：This note describes a dimethyl dicarbonate-assisted, Pd-(OAc)(2)/PPh3-catalyzed acylative Suzuki coupling of carboxylic acids with diarylborinic acids or tetraarylboronates for practical and efficient synthesis of sterically undemanding aryl ketones at room temperature. More than just cost-effective alternatives to aryl boronic acids, diarylborinic acids and tetraarylboronates displayed higher reactivity in the acylative Suzuki coupling. A variety of alkyl aryl ketones, including those bearing a hydroxy, bromo, or carbonyl group, could be readily obtained in modest to excellent yields.