文献类型：期刊文献

英文题名：Preparation of acrylamide-based poly-HIPEs with enhanced mechanical strength using PVDBM-b-PEG-emulsified CO2-in-water emulsions

作者：Wang, Liwen[1];Liu, Yongjia[2];Bao, Lei[1];Hu, Dongdong[1];Zong, Yuan[1];Tong, Gangsheng[2];Zhao, Ling[1];Liu, Tao[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Multiphase Mat Chem Engn, Shanghai 200237, Peoples R China;[2]Shanghai Jiao Tong Univ, Instrumental Anal Ctr, Shanghai 200240, Peoples R China

年份：2018

卷号：135

期号：23

外文期刊名：JOURNAL OF APPLIED POLYMER SCIENCE

收录：;EI(收录号：20180904837725);WOS:【SCI-EXPANDED(收录号:WOS:000427252800017)】；

基金：The authors are grateful to the National Science Foundation of China (21676081).

语种：英文

外文关键词：bioengineering; emulsion polymerization; mechanical properties; porous materials; surfactants

摘要：Poly(vinyl acetate-alt-dibutyl maleate)-block-poly(ethylene glycol) (PVDBM-b-PEG) copolymers were synthesized via reversible addition-fragmentation chain transfer radical polymerization and used as emulsifiers to form stable CO2-in-water high internal phase emulsions (C/W HIPEs). Then, highly interconnected cellular polyacrylamide (PAM) and poly(acrylamide-co-N-hydroxymethyl acrylamide) [P(AM-co-HMAM)] poly-HIPEs with enhanced mechanical strength were prepared based on the stable C/W HIPEs. The porous structures of the PAM poly-HIPEs, as well as morphology and compressive modulus, could be influenced by the surfactant concentration and the length of the CO2-philic tails of the surfactants. PAM poly-HIPEs with the smallest average pore diameter (11.12 +/- 0.62m) and the highest compressive modulus (22.65 +/- 0.10 MPa) could be obtained by using the short CO2-philic chains of the PVDBM-b-PEG surfactant at a high concentration (1.0 wt %). Moreover, with the copolymerization of N-hydroxymethyl acrylamide (HMAM) comonomers with acrylamide, the compressive modulus of the obtained P(AM-co-HMAM) poly-HIPEs was three times higher than that of PAM poly-HIPEs. Both PAM and P(AM-co-HMAM) poly-HIPEs were employed as scaffolds to guide H9c2 cardiac muscle cellular growth. Fluorescence images showed that a smaller average pore size and a narrower pore-size distribution were helpful for cell growth and proliferation on these materials. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46346.