文献类型：期刊文献

英文题名：Diastereo- and Enantioselective Construction of Oxindole-Fused Spirotetrahydrofuran Scaffolds through Palladium-Catalyzed Asymmetric [3+2] Cycloaddition of Vinyl Cyclopropanes and Isatins

作者：Mei, Liang-yong[1,2];Wei, Yin[3];Xu, Qin[1,2];Shi, Min[1,2,3]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2013

卷号：32

期号：12

起止页码：3544

外文期刊名：ORGANOMETALLICS

收录：;EI(收录号：20132716467729);WOS:【SCI-EXPANDED(收录号:WOS:000321074500014)，CCR-EXPANDED(收录号:WOS:000321074500014)】；

基金：We thank the Shanghai Municipal Committee of Science and Technology (11JC1402600), National Basic Research Program of China ((973)-2010CB833302), the Fundamental Research Funds for the Central Universities, and the National Natural Science Foundation of China for financial support (20902019, 20872162, 20672127, 21121062, 21102166, 20732008, 20772030, and 20702059).

语种：英文

外文关键词：Phosphorus compounds - Ligands - Palladium - Enantioselectivity - Propane

摘要：A novel asymmetric formal [3+2] cycloaddition of vinyl cyclopropanes and isatins in the presence of Pd-2(dba)(3) and the chiral imidazoline-phosphine ligand (aS,R,R)-L3 has been developed, affording the corresponding highly functionalized oxindole-fused spirotetrahydrofuran frameworks in good yields along with good diastereo- and high enantioselectivities under mild conditions.