文献类型：专利

英文题名：Bio-enzyme (e.g. trypsin) immobilization paramagnetic aldehyde-based mesoporous molecular sieve is prepared by covalently binding surface-modified superparamagnetic iron oxide nanoparticles with aldehyde functional group in molecular sieve

作者：CHENLIN Y;GAO Z;GUO Y;LU G;WANG J;ZHANG Z;YANG L;ZHAN W

机构：[1]UNIV EAST CHINA SCI&TECHNOLOGY

申请号：CN102703412-A

申请日：2012-06-06

公开日：2012-10-03

语种：英文

收录：DERWENT

摘要：NOVELTY - Bio-enzyme immobilization paramagnetic aldehyde-based mesoporous molecular sieve is prepared by using gamma -aldehyde propyltrimethoxysilane for introducing aldehyde functional group in inner and outer surfaces of mesoporous molecular sieve; modifying the surface of superparamagnetic iron oxide (Fe3O4) nanoparticles with gamma -aminopropylalkoxysilane; and covalently binding with the aldehyde group, where particle size of superparamagnetic Fe3O4 nanoparticles is larger than the pore size of molecular sieve. USE - Paramagnetic aldehyde-based mesoporous molecular sieve for immobilization of bio-enzyme i.e. penicillin acylase, glucose isomerase, trypsin, or amylase (all claimed). ADVANTAGE - The molecular sieve achieves improved performance and efficiency of immobilized enzyme. The activity of immobilized penicillin acylase is 9901 units/g, where after 10 cycles, 91.2% of the initial activity is kept.