文献类型：期刊文献

中文题名：大孔弱酸树脂对卡那霉素的吸附行为

英文题名：Extraction Characteristics of Kanamycin with Macroreticular Weak-Acid Exchange Resin

作者：严希康[1];赵丽[1];仇月霜[1];杨雅琴[1];沈林南[1]

机构：[1]华东理工大学生化工程研究所

年份：1994

卷号：20

期号：2

起止页码：163

中文期刊名：华东理工大学学报（自然科学版）

外文期刊名：Journal of East China University of Science and Technology

收录：CSTPCD;;国家哲学社会科学学术期刊数据库;EI(收录号：1994121437903);Scopus;CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：抗菌素;卡那霉素;大孔弱酸树脂

外文关键词：antibiotics;Kanamycin;sorption;ion-exchange capacity;elution;macroreti-cular structure ion exchange resins

摘要：比较了大孔弱酸树脂（Ａ）和强酸７３２树脂（Ｂ）对卡那霉素（Ｃ）的吸附行为。用正交设计试验法和电子计算机演算，确定了最适工艺条件，并用发酵液做了动态试验。实验表明，Ａ型华化－Ⅲ湿树脂对Ｃ成品溶液的静态交换容量为２４．２×１０￣７ｕ／Ｌ，比Ｂ提高了２５．４％；对Ｃ发酵液的动态交换容量为１５．７×１０￣７ｕ／Ｌ，比Ｂ提高了２２．７％，同样比ＡｍｂｅｒｌｉｔｅＩＲＣ－５０树脂也高。在滤液呈中性条件下，浓度为９９×１０￣５ｕ／Ｌ左右时吸附，用２．５％氨水解吸，可获得Ｃ离子交换过程最佳状态，回收率增加、浓缩倍数提高、能耗降低。
The extraction characteristics,sorption capacity and elution property,of Ka-namycin with macroreticular wcak-acid exchange resin(Ⅰ)and the conventional strong-acidrcsin 732 were compared, The optimum technological conditions of extraction by(Ⅰ)werestudied by means of orthogonal design and theoretical calculation with computer. The columntest for fermentalion broth as processed.Experimental results showed that the optimum statusfor Kanamycin ion-exchange process is under the conditions: the neutral filtrat of fermentationbroth with Kanamycin concentiation of 99 ×10￣5 u/L and 2.5%aqueous ammonia as eluent.This method has following advantages: Huahua macroreticular weak-acid resin-Ⅲ possessesthe higher sorption capacity than 732 resin and Amberlite IRC-50 resin,the overall yeild ofKanamycin is increased,concentractive times are reised and the energy consumption is de-creased.