文献类型：期刊文献

英文题名：Sulfonated porous surface of tantalum pentoxide/polyimide composite with micro-submicro structures displaying antibacterial performances and stimulating cell responses

作者：Asadullah, Syed[1,4];Mei, Shiqi[1];Wang, Deqiang[1];Yao, Yuan[1];Pan, Yongkang[1];Wang, Dongliang[2];Guo, Han[3];Wei, Jie[1]

机构：[1]East China Univ Sci & Technol, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[2]Xinhua Hosp, Shanghai Jiao Tong Sch Med, Dept Orthoped Surg, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China;[3]Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai Synchrotron Radiat Facil, 239 Zhangheng Rd, Shanghai 201204, Peoples R China;[4]Univ Lahore, Dept Phys, Lahore, Pakistan

年份：2020

卷号：190

外文期刊名：MATERIALS & DESIGN

收录：;EI(收录号：20200708183420);WOS:【SCI-EXPANDED(收录号:WOS:000524744700034)】；

基金：The grants were from The National Natural Science Foundation of China (81771990, 11575115 and 81771790,) and KeyMedical Program of Science and Technology Development of Shanghai (19441906100, 17441900600 and 17441902000).

语种：英文

外文关键词：Tantalum pentoxide; Polyimide based composite; Sulfonation; Micro-submicro structures; Antibacterial performances

摘要：To improve the surface bio-performances of polyimide (PI), tantalum pentoxide (Ta2O5)/PI composites (TPC) were prepared, and concentrated sulfuric acid was utilized to modify TPC surface. The results revealed that sulfonated TPC (STPC) exhibited microporous surface with pores size of about 3 mu m, and sulfonic acid (-SO3H) groups were introduced onto the microporous surface. In addition, many Ta2O5 submicro particles appeared on the microporous surface, which formed micro-submicro structures. Compared with PI, the surface roughness, hydrophilicity, surface energy and protein adsorption as well as apatite mineralization of STPC in simulated body fluid were obviously enhanced, which increased with Ta2O5 content increasing. In addition, STPC exhibited antibacterial performances due to the presence of SO3H groups and Ta2O5. Furthermore, the responses (adhesion, proliferation and differentiation) of rat bone marrow mesenchymal stem cells to STPC were remarkably promoted with the increase of Ta2O5 content. In short, STPC with 50w% Ta2O5 content (STPC 50) with sulfonated microporous surface contained micro-submicro structures, which exhibited antibacterial performances and stimulated cell responses. STPC50 with improved surface properties and cylocompatibility might have large potentials for bone repair applications. (C) 2020 Published by Elsevier Ltd.