文献类型：期刊文献

英文题名：Facile synthesis of 2-fluoroindenones via a Knoevenagel condensation/palladium-catalyzed annulation

作者：Su, Yue[1,2];Fang, Xiang[1,2];Zhou, Jun[1,2,3];Bian, Yizhen;Yang, Xueyan[1,2];Wu, Fanhong[4]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 20023Z, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, 130 Meilong Rd, Shanghai 20023Z, Peoples R China;[3]East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China;[4]Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China

年份：2018

卷号：211

起止页码：76

外文期刊名：JOURNAL OF FLUORINE CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000435061600008)，CCR-EXPANDED(收录号:WOS:000435061600008)】；

基金：The authors thank the National Natural Science Foundation of China (No. 21672151) for financial support.

语种：英文

外文关键词：2-Fluoroindenones; Domino reaction; Knoevenagel condensation; Intramolecular heck cyclization

摘要：An efficient synthesis of 2-fluoroindenones was developed starting from simple o-bromo-2-fluroethenones and aldehydes. This domino reaction involved Knoevenagel condensation and intramolecular Heck coupling cyclization. A variety of 2-fluoroindenones were generated in good to excellent yields.