文献类型：期刊文献

英文题名：A simple, fast and low-cost turn-on fluorescence method for dopamine detection using in situ reaction

作者：Zhang, Xiulan[1];Zhu, Yonggang[2];Li, Xie[1];Guo, Xuhong[1,3];Zhang, Bo[4];Jia, Xin[1];Dai, Bin[1]

机构：[1]Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan,En, Key Lab Mat Oriented Chem Engn Xinjiang Uygur Aut, Shihezi 832003, Peoples R China;[2]CSIRO Mfg, Microfluid & Fluid Dynam Lab, Private Bag 10, Clayton, Vic 3168, Australia;[3]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[4]Shihezi Univ, Sch Pharm, Minist Educ, Key Lab Xinjiang Phytomed Resources, Shihezi 832000, Peoples R China

年份：2016

卷号：944

起止页码：51

外文期刊名：ANALYTICA CHIMICA ACTA

收录：;EI(收录号：20164402969943);WOS:【SCI-EXPANDED(收录号:WOS:000385841200006)】；

基金：This work is supported by Natural Science Foundation of China (21264013, 21364010). X. Zhang also acknowledges CSIRO Manufacturing, Clayton, Melbourne Australia, for providing the support during her stay at the Microfluids and Fluid Dynamics Group.

语种：英文

外文关键词：Resorcinol; Dopamine detection; Azamonardine; Turn-on fluorescence

摘要：A simple, fast and low-cost method for dopamine (DA) detection based on turn-on fluorescence using resorcinol is developed. The rapid reaction between resorcinol and DA allows the detection to be performed within 5 min, and the reaction product (azamonardine) with high quantum yield generates strong fluorescence signal for sensitive optical detection. The detection exhibits a high sensitivity to DA with a wide linear range of 10 nM-20 mu M and the limit of detection is estimated to be 1.8 nM (S/N = 3). This approach has been successfully applied to determine DA concentrations in human urine samples with satisfactory quantitative recovery of 97.84%-103.50%, which shows great potential in clinical diagnosis. (C) 2016 Elsevier B.V. All rights reserved.