文献类型：期刊文献

中文题名：均匀设计优选微波辅助萃取何首乌中有效成分的研究

英文题名：Study on optimization of microwave-assisted extraction process for active ingredients in Radix Polygoni Multiflori with uniform design

作者：王娟[1];沈平孃[2];沈永嘉[1]

机构：[1]华东理工大学化学与制药学院,上海200237;[2]国家中药制药工程技术研究中心,上海201203

年份：2003

卷号：34

期号：4

起止页码：314

中文期刊名：中草药

外文期刊名：Chinese Traditional and Herbal Drugs

收录：CSTPCD;;Scopus;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

基金：国家重点科技攻关项目 ( 99-92 9-0 2 -14 )

语种：中文

中文关键词：均匀设计;优选;微波辅助萃取;何首乌;有效成分;研究

外文关键词：Radix Polygoni Multiflori; stilbene glucoside; microwave-assisted extraction; uniform design

摘要：目的　研究微波辅助萃取何首乌的提取工艺。方法　以总蒽醌和 2 ,3,5 ,4′-四羟基二苯乙烯 - 2 - O-β- D -葡萄糖苷 (二苯乙烯苷 )的含量为指标 ,通过均匀设计的方法 ,采用连续微波辐射方法进行微波萃取工艺的优化。结果　微波功率、微波辐射时间、溶剂浓度、溶剂用量、原料浸泡时间对何首乌中有效成分的提取具有交互作用 ,优选出的最佳工艺条件为 :微波功率 340 W、微波辐射时间 10 min、溶剂乙醇浓度 95 %、固液比为 1∶ 5、浸泡时间 1h。结论　通过验证实验表明 ,所建立的数学模型是合理的。
Object To study the microwave-assisted extraction process of Radix Polygoni Multiflori. Methods Using the uniform design, the optimization process of microwave-assisted extraction for total anthraquinones and 2, 3, 5, 4′- tetrahydroxystilbene-2-O-β-D-glucoside in Radix Polygoni Multiflori was gained by continuous microwave radiation. Results Some parameters, such as microwave power, radiation time, solvent concentration, solvent consumption and dipping time had interactions to the extraction of active ingredients in Radix Polygoni Multiflori. The best optimization process was obtained as following: 340 W as the microwave power, 10 min as the radiation time, 95% ethanol as the solvent, 1∶5 as the proportion of solid to liquid and 1 h as the dipping time. Conclusion The established models were proved to be reasonable by the verified experiment.