文献类型：期刊文献

英文题名：A FACILE SYNTHESIS OF PYRIMIDONE DERIVATIVES AND SINGLE-CRYSTAL CHARACTERIZATION OF PYMETROZINE

作者：Wang, Baozhu[1];Ke, Shaoyong[1];Kishore, Babu[1];Xu, Xiaoyong[1];Zou, Zhuyan[1];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2012

卷号：42

期号：16

起止页码：2327

外文期刊名：SYNTHETIC COMMUNICATIONS

收录：;EI(收录号：20242716622163);WOS:【SCI-EXPANDED(收录号:WOS:000304324100001)，CCR-EXPANDED(收录号:WOS:000304324100001)】；

基金：This work was financial supported by National Basic Research Program of China (973 Program, 2010CB126100), National High Technology Research, Development Program of China (863 Program, 2011AA10A207), Key Projects in the National Science and Technology Pillar Program during the Twelfth Five-Year Plan Period (2011BAE06B01) and National Science Foundation China Program Grant (20872034), and Program for New Century Excellent Talents in University (NCET070284). This work was also partly supported by Shanghai Foundation of Science and Technology (08391911600, 0XD1401300, 073919107) and Shanghai Leading Academic Discipline Project, Project No. B507, and 111 Project (No. B07023).

语种：英文

外文关键词：Crystal; pymetrozine; pyrimidone; synthesis

摘要：A facile and efficient synthetic methodology for the preparation of aza-pyrimidone and beno-pyrimidone derivatives is described, in which the triazinone ring and dihydroquinazolin-2(1H)-one was convenient constructed. The structures of all the newly synthesized compounds were characterized by mass, H-1 NMR, and infrared spectroscopy. In additional, the crystal of pymetrozine was obtained to find useful information such as configuration and molecular action mechanisms.