文献类型：期刊文献

英文题名：De Novo Construction of Catenanes with Dissymmetric Cages by Space-Discriminative Post-Assembly Modification

作者：Li Pan[1];Xu Shijun[2];Yu Chunyang[1];Li Zi-Ying[2];Xu Jianping[1];Li Zi-Mu[1];Zou Lingyi[1];Leng Xuebing[4];Gao Shan[5];Liu Zhiqiang[3];Liu Xiaoyun[2];Zhang Shaodong[1]

机构：[1]Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai Key Lab Elect Insulat & Thermal Aging, Frontiers Sci Ctr Transformat Mol, 800 Dongchuan Rd, Shanghai 200240, Peoples R China;[2]East China Univ Sci & Technol, Key Lab Specially Funct Polymer Mat & Related Tec, Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Zhejiang Univ Technol, Natl & Local Joint Engn Res Ctr Biomfg Chiral Che, Hangzhou 310014, Peoples R China;[4]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China;[5]Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6, Dept Neurol, South Campus, Shanghai 200240, Peoples R China

年份：2020

卷号：59

期号：18

起止页码：7113

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20201108284379);WOS:【SCI-EXPANDED(收录号:WOS:000526818900021)】；

语种：英文

外文关键词：catenanes; interlocked cages; reduction; structural topology; supramolecular chemistry

摘要：Considerable efforts have been made to increase the topological complexity of mechanically interlocked molecules over the years. Three-dimensional catenated structures composed of two or several (usually symmetrical) cages are one representative example. However, owing to the lack of an efficient universal synthetic strategy, interlocked structures made up of dissymmetric cages are relatively rare. Since the space volume of the inner cavity of an interlocked structure is smaller than that outside it, we developed a novel synthetic approach with the voluminous reductant NaBH(OAc)(3) that discriminates this space difference, and therefore selectively reduces the outer surface of a catenated dimer composed of two symmetric cages, thus yielding the corresponding catenane with dissymmetric cages. Insight into the template effect that facilitates the catenation of cages was provided by computational and experimental techniques.