文献类型：期刊文献

英文题名：Direct copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids with AgSCF3

作者：Wu, Wei[1];Wang, Biyun[1];Ji, Xinfei[1];Cao, Song[1]

机构：[1]ECUST, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2017

卷号：4

期号：7

起止页码：1299

外文期刊名：ORGANIC CHEMISTRY FRONTIERS

收录：;EI(收录号：20184806136992);WOS:【SCI-EXPANDED(收录号:WOS:000405863700015)，CCR-EXPANDED(收录号:WOS:000405863700015)】；

基金：Financial support from the National Natural Science Foundation of China (Grant No. 21472043 and 21272070) is gratefully acknowledged.

语种：英文

外文关键词：Catalysis - Sulfur compounds - Copper - Silver compounds

摘要：A copper-catalyzed direct oxidative trifluoromethylthiolation of aryl boronic acids with AgSCF3 has been developed. This approach provides straightforward and efficient access to a variety of aryl trifluoromethyl sulfides from an easily prepared and stable nucleophilic trifluoromethylthiolation reagent AgSCF3, and readily available nucleophilic aryl boronic acids, thus avoiding the preparation of electrophilic trifluoromethylthiolating reagents in advance. Preliminary mechanistic experiments indicated that AgSCF3 served as both a source of SCF3 and an oxidant.