文献类型：期刊文献

英文题名：Conformation Study of Dual Stimuli-Responsive Core-Shell Diblock Polymer Brushes

作者：Chen, Kaimin[1];Cao, Lan[2];Zhang, Ying[2];Li, Kai[1];Qin, Xue[2];Guo, Xuhong[2]

机构：[1]Shanghai Univ Engn Sci, Coll Chem & Chem Engn, Shanghai 201620, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem Engn, State Key Lab Chem Engn, Shanghai 200237, Peoples R China

年份：2018

卷号：10

期号：10

外文期刊名：POLYMERS

收录：;EI(收录号：20184005897278);WOS:【SCI-EXPANDED(收录号:WOS:000448662400039)】；

基金：This research was funded by National Natural Science Foundation of China grant number 21504052, National Natural Science Foundation of China grant number 5171101370, National Natural Science Foundation of China grant number 21476143 and Shanghai Sailing Program grant number 15YF1404800.

语种：英文

外文关键词：stimuli-response; polymer brush; polyelectrolyte; bovine serum albumin

摘要：Stimuli-responsive nanoparticles are among the most popular research topics. In this study, two types of core-shell (polystyrene with a photoiniferter (PSV) as the core and diblock as the shell) polymer brushes (PSV@PNIPA-b-PAA and PSV@PAA-b-PNIPA) were designed and prepared using surface-initiated photoiniferter-mediated polymerization (SI-PIMP). Moreover, their pH- and temperature-stimuli responses were explored by dynamic light scattering (DLS) and turbidimeter under various conditions. The results showed that the conformational change was determined on the basis of the competition among electrostatic repulsion, hydrophobic interaction, hydrogen bonding, and steric hindrance, which was also confirmed by protein adsorption experiments. These results are not only helpful for the design and synthesis of stimuli-responsive polymer brushes but also shed light on controlled protein immobilization under mild conditions.