文献类型：期刊文献

英文题名：Multimodal Use of New Coumarin-Based Fluorescent Chemosensors: Towards Highly Selective Optical Sensors for Hg2+ Probing

作者：Bazzicalupi, Carla[1];Caltagirone, Claudia[2];Cao, Zenfeng[3,4];Chen, Qibin[4];Di Natale, Corrado[5];Garau, Alessandra[2];Lippolis, Vito[2];Lvova, Larisa[3,6];Liu, Honglai[4];Lundstrom, Ingemar[7];Mostallino, M. Cristina[8];Nieddu, Mattia[2];Paolesse, Roberto[3];Prodi, Luca[9];Sgarzi, Massimo[9];Zaccheroni, Nelsi[9]

机构：[1]Univ Florence, Dipartimento Chim Ugo Shiff, I-50019 Florence, Italy;[2]Univ Cagliari, Dipartimento Sci Chim & Geol, I-09042 Monserrato, CA, Italy;[3]Univ Roma Tor Vergata, Dipartimento Sci & Tecnol Chim, I-00133 Rome, Italy;[4]E China Univ Sci & Technol, Dept Chem & Mol Engn, Shanghai 200237, Peoples R China;[5]Univ Roma Tor Vergata, Dipartimento Ingn Elettron, I-00133 Rome, Italy;[6]St Petersburg State Univ, Fac Biol & Soil Sci, St Petersburg 199034, Russia;[7]Linkoping Univ, IFM, Dept Phys Chem & Biol, S-58183 Linkoping, Sweden;[8]Ist Neurosci CNR Cagliari, I-09042 Monserrato, CA, Italy;[9]Univ Bologna, Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

年份：2013

卷号：19

期号：43

起止页码：14639

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20134316880638);WOS:【SCI-EXPANDED(收录号:WOS:000330288400026)】；

基金：MIUR is gratefully acknowledged for financial support (Project PRIN 2009Z9ASCA). The authors acknowledge Dr. P. Massanisso, Dr. C. Cremisini, and in particular, Dr. E. Nardi from ENEA C. R. Casaccia, UTPRA-GEOC, Rome, Italy for DMA mercury(II) content determination in natural water samples.

语种：英文

外文关键词：coumarins; fluorescent probes; mercury; nanoparticles; sensors

摘要：Despite several types of fluorescent sensing molecules have been proposed and examined to signal Hg2+ ion binding, the development of fluorescence-based devices for in-field Hg2+ detection and screening in environmental and industrial samples is still a challenging task. Herein, we report the synthesis and characterization of three new coumarin-based fluorescent chemosensors featuring mixed thia/aza macrocyclic framework as receptors units, that is, ligands L1-L3. These probes revealed an OFF-ON selective response to the presence of Hg2+ ions in MeCN/H2O 4:1 (v/v), which allowed imaging of this metal ion in Cos-7 cells in vitro. Once included in silica core-polyethylene glycol (PEG) shell nanoparticles or supported on polyvinyl chloride (PVC)-based polymeric membranes, ligands L1-L3 can also selectively sense Hg2+ ions in pure water. In particular we have developed an optical sensing array tacking advantage of the fluorescent properties of ligand L3 and based on the computer screen photo assisted technique (CSPT). In the device ligand L3 is dispersed into PVC membranes and it quantitatively responds to Hg2+ ions in natural water samples.