文献类型：期刊文献

中文题名：Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation

英文题名：Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation

作者：Gao-Lei Wang[1];Xi Chen[1];Ya-Ning Chang[1];Dan Du[1];Zhong Li[1,2];Xiao-Yong Xu[1,2,3]

机构：[1]Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology;[2]Shanghai Collaborative Innovation Center for Biomanufacturing Technology;[3]East China University of Science and Technology,Shanghai Key Laboratory of Chemical Biology, School of Pharmacy

年份：2015

卷号：26

期号：12

起止页码：1502

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2015_2016】；PubMed;

基金：financial supported by the National High Technology Research and Development Program of China(National 863 Program,No.2013AA065202);the National Natural Science Foundation of China(No.21272071);supported by the Special Fund for Agro-scientific Research in the Public Interest(No.201103007);the Fundamental Research Funds for the Central Universities

语种：英文

中文关键词：Meloidogyne incognita displayed endowed moderate implied potent crops removed afford

外文关键词：Meloidogyne incognita displayed endowed moderate implied potent crops removed afford

摘要：To discover new chemotypes of nematicides with proper toxicological profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 6k and 6p displayed 100%inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides.
To discover new chemotypes of nematicides with proper toxicological profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 6k and 6p displayed 100%inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides.