文献类型：期刊文献

英文题名：Detection of Dynabeads in small bias magnetic field by a micro fluxgate-based sensing system

作者：Lei, Chong[1];Sun, Xue-Cheng[1];Liu, Cui[2];Lei, Jian[1];Wang, Tao[1];Yang, Zhen[1];Zhou, Yong[1]

机构：[1]Shanghai Jiao Tong Univ, Sch Elect Informat & Elect Engn, Dept Micro Nano Elect, Key Lab Thin Film & Microfabricat,Minist Educ, Shanghai 200240, Peoples R China;[2]E China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China

年份：2014

卷号：116

期号：15

外文期刊名：JOURNAL OF APPLIED PHYSICS

收录：;EI(收录号：20144400137236);WOS:【SCI-EXPANDED(收录号:WOS:000344345400059)】；

基金：This work was supported by The National Natural Science Foundation of China (Grant Nos. 61074168 and 61273065), National Science and Technology Support Program (No. 2012BAK08B05), Natural Science Foundation of Shanghai (No. 13ZR1420800), and the Analytical and Testing Center in Shanghai Jiao Tong University.

语种：英文

外文关键词：MEMS - Coremaking - Magnetic fields - Biological materials

摘要：The micro fluxgate sensors have shown high sensitivity for the magnetic beads detection. For portable magnetic biological detection, Co-based amorphous ribbons with high permeability and low saturation magnetic induction are chosen as core materials to lower the operation requirements of the fluxgate-based magnetic beads detection. The micro fluxgate sensors with single-layer core and bi-layer core are fabricated by Micro-Electro-Mechanical System technologies, which exhibit a power consumption of 10.88 mW and 24.48 mW, a sensitivity of 1644 V/T and 1456 V/T, and a noise of 1.66 nT/Hz(1/2) @ 1Hz and 2.32 nT/Hz(1/2) @ 1Hz, respectively. The Dynabeads with concentrations of 300 lg/ml in 10 mu l are detected by the micro fluxgate-based sensing system based on static response, and the results show signal change ratio of 12.2% and 9.2% under the max signal difference at 215 mu T and 480 mu T of the bias magnetic field for two kinds of the sensors, respectively, which is near the saturation point of the sensors. The fluxgate-based bead detection system with Co-based ribbon core presents low demands for the bias magnetic field and power consumption. (C) 2014 AIP Publishing LLC.