文献类型：期刊文献

英文题名：Estimating the Mass of Pharmaceuticals Harbored in Municipal Solid Waste Landfills by Analyzing Refuse Samples at Various Ages and Depths

作者：Yu, Xia[1];Zhao, Wentao[3];Lyu, Shuguang[1,2];Cai, Zhenxiao[4];Yu, Gang[5];Wang, Hualin[1];Barcelo, Damia[6];Sui, Qian[1,2]

机构：[1]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China;[3]Tongji Univ, Coll Environm Sci & Engn, State Key Lab Pollut Control & Resource Reuse, Shanghai 200092, Peoples R China;[4]Univ Washington, MicroHAOPs Inc, Seattle, WA 98195 USA;[5]Tsinghua Univ, Sch Environm, Beijing 100084, Peoples R China;[6]Spanish Council Sci Res CSIC, Inst Environm Assessment & Water Res, Dept Environm Chem, Barcelona 08034, Spain

年份：2023

卷号：57

期号：15

起止页码：6063

外文期刊名：ENVIRONMENTAL SCIENCE & TECHNOLOGY

收录：;EI(收录号：20231413845286);WOS:【SCI-EXPANDED(收录号:WOS:000962866800001)】；

基金：This research was partly supported by the National Natural Science Foundation of China (21777042, 22076045, 21577033) , the Science and Technology Commission of Shanghai Municipality's Yangfan Special Project (23YF1408400) , Shanghai Talent Development Funding (2020051) , Shanghai Youth Talent Support Program, the Open Research Fund of State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals (2022KFYB03) , and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：contaminants of emerging concern (CECs); municipal solid wastes (MSWs); temporal variations; pharmaceutical mass; monte Carlo analysis

摘要：Pharmaceuticals have been detected at high concen-trations in municipal solid waste (MSW) landfill leachates, which are recognized as an underestimated source of pharmaceutical residues in the environment. However, limited efforts have been made to characterize pharmaceuticals in MSW landfill refuse, which is also of significant concern given the potential long-term environmental impact. Herein, we excavated landfill refuse from six cells with landfill ages of 7-27 years in the largest MSW landfill in Shanghai (in each cell, landfill refuse was collected from different depths of 2-8 m) and analyzed samples for the presence of 55 pharmaceuticals, including antibiotics and non-antibiotics. The results reveal the presence of 42 pharmaceuticals in landfill refuse, with median concentrations ranging from 0.30 to 116 mu g/kg. Antibiotic and non-antibiotic pharmaceuticals exhibited diverse concentration trends with age, related to changes in policy intervention and consumption over time. Different concentration variations of individual pharmaceuticals were observed in refuse samples excavated at different depths and positively correlated to their sorption ability. The mass of pharmaceuticals in the investigated landfill was estimated from the obtained concentrations to be 80-220 tons with 95% probability, based on Monte Carlo analysis. To the best of our knowledge, this study provides the first estimate of pharmaceutical mass in an MSW landfill. The results will be helpful for understanding the potential long-term environmental impact of pharmaceuticals in landfills.