文献类型：期刊文献

英文题名：Preparation of hollow silica nanoparticles using cationic spherical polyelectrolyte brushes as catalytic template

作者：Fu, Zhinan[1,2];Zhou, Qian[1,2];Li, Li[1,2];Liu, Dianhua[1,2];Guo, Xuhong[1,2,3]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Engn Res Ctr Large Scale Reactor Engn & Technol, Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Int Joint Res Ctr Green Energy Chem Engn, Shanghai 200237, Peoples R China;[3]Shihezi Univ, Engn Res Ctr Mat Chem Engn Xinjiang Bingtuan, Xinjiang 832000, Peoples R China

年份：2020

卷号：298

期号：7

起止页码：879

外文期刊名：COLLOID AND POLYMER SCIENCE

收录：;EI(收录号：20201208318785);WOS:【SCI-EXPANDED(收录号:WOS:000546806100018)】；

语种：英文

外文关键词：Hollow silica nanoparticles; Spherical polyelectrolyte brushes; Catalytic template; Doxorubicin hydrochloride

摘要：This paper presents a facile procedure to fabricate uniform-sized hollow silica nanoparticles (SNP) under a mild condition by using cationic spherical polyelectrolyte brushes (SPB) with a polystyrene (PS) core and densely grafted poly(2-aminoethyl methacrylate hydrochloride) (PAEMH) brush shell as a catalytic template. By changing the brush layer thickness of SPB, hollow SNP with different silica shell thickness could be easily obtained. This method provides a new way for the preparation of hollow SNP without additional catalyst. The obtained hollow SNP exhibited a high-drug encapsulation efficiency (80%) for doxorubicin hydrochloride (DOX), should be of significance in the fields of drug delivery, cancer therapy, and bioimaging.