文献类型：期刊文献

中文题名：Synthesis of Fluoroalkylated Allylic-β-hydroxyesters and Fluoroalkylated ,β,γ-Epoxy Esters from Ethyl 3-Hydroxy-4-pentenoate

英文题名：Synthesis of Fluoroalkylated Allylic-β-hydroxyesters and Fluoroalkylated ,β,γ-Epoxy Esters from Ethyl 3-Hydroxy-4-pentenoate

作者：方向[1];熊英[1];王琼[1];赵敏[1];吴范宏[1,2]

机构：[1]Laboratory for Advanced Material and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China;[2]School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 200235, China

年份：2011

卷号：29

期号：12

起止页码：2669

中文期刊名：Chinese Journal of Chemistry

外文期刊名：中国化学（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2011_2012】；

基金：project supported by the National Natural Science Foundation of China （NNSFC） （Nos. 20972050, 21172148）.

语种：中文

中文关键词：ethyl 3-hydroxy-4-pentenoate;fluoroalkylated allylic-β-hydroxyesters;fluoroalkylated β,γ-epoxy esters

外文关键词：ethyl 3-hydroxy-4-pentenoate, fluoroalkylated allylic-β-hydroxyesters, fluoroalkylated β,γ-epoxy esters

摘要：A sequential transformation of fluoroalkylated adducts obtained from ethyl 3-hydroxy-4-pentenoate with fluorinated iodides was reported. The dehydrohalogenation of adducts was favored to give fluoroalkylated unsaturated β-hydroxy esters in the presence of triethylamine. And intramolecular SN42 reaction products, fluoroalkylated β,γ-epoxy esters, were obtained in 10% aqueous sodium carbonate solution.
A sequential transformation of fluoroalkylated adducts obtained from ethyl 3-hydroxy-4-pentenoate with fluorinated iodides was reported. The dehydrohalogenation of adducts was favored to give fluoroalkylated unsaturated β-hydroxy esters in the presence of triethylamine. And intramolecular SN42 reaction products, fluoroalkylated β,γ-epoxy esters, were obtained in 10% aqueous sodium carbonate solution.