文献类型：期刊文献

英文题名：Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography

作者：Jin, Yu[1]; Liang, Tu[1]; Fu, Qing[1]; Xiao, Yuan-Sheng[1]; Feng, Jia-Tao[1]; Ke, Yan-Xiong[2]; Liang, Xin-Miao[1,2]

机构：[1] Dalian Institute of Chemical Physics, Graduate School, the Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, 116023, China; [2] School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China

年份：2009

卷号：1216

期号：11

起止页码：2136

外文期刊名：Journal of Chromatography A

收录：EI(收录号：20090911924213)

语种：英文

外文关键词：Hydrophilicity - Liquid chromatography - Liquids - Quality assurance - Chromatographic analysis - Medicine

摘要：Fingerprint analysis is considered one of the most powerful approaches to quality control in traditional Chinese medicines (TCMs). In this study, a binary chromatographic fingerprint analysis was developed using hydrophilic interaction chromatography (HILIC) and reversed-phase liquid chromatography (RPLC) to gain more chemical information about polar compounds and weakly polar compounds. This method was used to construct a chromatographic fingerprint of Ligusticum chuanxiong. The two chromatographic methods demonstrated good precision, reproducibility, and stability, with relative standard deviations of