文献类型：期刊文献

中文题名：酶-有机金属催化合成阳离子聚己内酯

英文题名：Enzyme-Organometallics Catalyzed Synthesis of Cationic Polycaprolactone

作者：汪冬[1];肖艳[1]

机构：[1]华东理工大学材料科学与工程学院,上海200237

年份：2017

卷号：30

期号：4

起止页码：450

中文期刊名：功能高分子学报

外文期刊名：Journal of Functional Polymers

收录：北大核心:【北大核心2014】；CSCD:【CSCD2017_2018】；

基金：上海市"科技创新行动计划"国际合作项目(14520720600)

语种：中文

中文关键词：哌啶内酯;Novozym;435;开环聚合

外文关键词：piperidine lactone;Novozym 435;ring-opening polymerization

摘要：首先以4-甲酸苄基哌啶内酯(NPIL)为原料,采用钯碳(Pd-C)催化加氢脱保护的方法合成了4-哌啶内酯单体(PIL);然后以苯甲醇为引发剂,分别采用酶(Novozym 435)和异辛酸亚锡(Sn(Oct)_2)催化己内酯(CL)和PIL开环聚合,制备了阳离子共聚物聚(4-哌啶内酯)-co-聚己内酯(P(PIL-co-CL))。通过核磁共振氢谱(~1H-NMR)、红外光谱(FT-IR)、凝胶渗透色谱(GPC)、差示扫描量热仪(DSC)等方法对共聚物的结构组成、数均分子量以及热性能等进行了表征。结果表明:成功制备了阳离子聚合物P(PIL-co-CL),相较于有机金属催化剂Sn(Oct)_2,固定化酶Novozym435催化内酯开环聚合表现出聚合可控且无副反应的优点。
4-Piperidine lactone（PIL） was first synthesized by palladium carbon（Pd-C）catalytic hydrogenolysis using 4-acid benzyl piperidine lactone（NPIL）as the monomer.The cationic poly（4-piperdine lactone-co-caprolactone）（P（PIL-co-CL））copolymers were further synthesized by enzyme or organometallics catalyzed ring-opening polymerization with benzyl alcohol as initiator,PIL and CL as monomers.The structure,molecular weight and thermal properties of copolymers were characterized by Nuclear Magnetic Resonance spectroscopy（1H-NMR）,Fourier Transform Infrared spectroscopy（FTIR）,Gel Permeation Chromatography（GPC）and Differential Scanning Calorimetry（DSC）,etc.Results showed that the cationic P（PIL-co-CL）copolymers were synthesized successfully.Compared with organometallic catalyst Sn（Oct）2,the immobilized enzyme Novozym 435 had the advantages of controllable polymerization and no side reaction.