文献类型：期刊文献

中文题名：Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

作者：Rui Xiong[2];Leike Zhang[3];Shiliang Li[2];Yuan Sun[3];Minyi Ding[2];Yong Wang[1];Yongliang Zhao[1];Yan Wu[3];Weijuan Shang[3];Xiaming Jiang[3];Jiwei Shan[2];Zihao Shen[2];Yi Tong[2];Liuxin Xu[2];Yu Chen[1];Yingle Liu[1];Gang Zou[4];Dimitri Lavillete[4];Zhenjiang Zhao[2];Rui Wang[2];Lili Zhu[2];Gengfu Xiao[3];Ke Lan[1];Honglin Li[2];Ke Xu[1,4]

机构：[1]State Key Laboratory of Virology,College of Life Sciences,Wuhan University,Wuhan 430072,China;[2]Shanghai Key Laboratory of New Drug Design,State Key Laboratory of Bioreactor Engineering,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China;[3]State Key Laboratory of Virology,Wuhan Institute of Virology,Center for Biosafety Mega-Science,Chinese Academy of Sciences,Wuhan 430071,China;[4]CAS Key Laboratory of Molecular Virology and Immunology,Institut Pasteur of Shanghai,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200031,China

年份：2021

卷号：12

期号：1

起止页码：76

中文期刊名：Protein & Cell

外文期刊名：蛋白质与细胞（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2021_2022】；PubMed;

语种：英文

中文关键词：Figure;discovery;ODH;

摘要：Figure 1.Discovery of novel and potent DHODHi and their anti-influenza A virus activities.(A)The discovery and design of S312 and S416.The detailed descriptions of the discovery workflow are in Method.Binding analysis of S312(B)and S416(C).Thermodynamic analysis of the binding of S312 and S416 to DHODH was carried out at 25 C on a MicroCal iTC200 instrument.Kinetic analysis of the binding of S312 and S416 to DHODH was performed with a Biacore T200 instrument.