文献类型：期刊文献

英文题名：Whole-Cell Biocatalytic Processes with Ionic Liquids

作者：Xu, Pei[1,3]; Zheng, Gao-Wei[2]; Du, Peng-Xuan[3]; Zong, Min-Hua[3]; Lou, Wen-Yong[1,3]

机构：[1] State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou, 510640, China; [2] State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China; [3] Laboratory of Applied Biocatalysis, School of Light Industry and Food Sciences, South China University of Technology, Guangzhou, 510640, China

年份：2016

卷号：4

期号：2

起止页码：371

外文期刊名：ACS Sustainable Chemistry and Engineering

收录：EI(收录号：20160601889718)

语种：英文

外文关键词：Catalysis - Cells - Cytology - Biodegradability - Ionic liquids - Enzymes

摘要：Whole-cell-based biocatalysis in ionic liquids (ILs)-containing systems has attracted increasing interest in recent years. Compared to bioreactions catalyzed by isolated enzymes, the major advantages of using whole cell in biocatalytic processes are that cells provide a natural intracellular environment for the enzymes to function with cofactors regeneration in situ. An increasing number of renewable ILs are now accessible as a result of the ongoing progress in designing strategy of ILs and the sustainable environment requirement. The toxicity of ILs to microbial cells and the biodegradability are two of the crucial factors that allow the biocatalysis in ILs being applied in practice rather than in bench-scale. Applications of whole-cell biocatalysis in IL-containing systems have, to date, been focused on the production of valuable compounds, mainly through reduction, oxidation, and hydrolytic reactions. The mechanism research of ILs affecting the whole-cell biocatalysis offers the possibility to integrate effectively ILs with biotransformation. Thus, a comprehensive understanding of the whole-cell-based biocatalytic process with ILs will contribute to the discovery of novel solvent for enzymatic reaction and the synthesis of more valuable compounds. ? 2015 American Chemical Society.