文献类型：期刊文献

英文题名：Supportless electrochemical sensor based on molecularly imprinted polymer modified nanoporous microrod for determination of dopamine at trace level

作者：Li, Yingchun[1,2];Song, Han[1];Zhang, Lu[1];Zuo, Peng[3];Ye, Bang-ce[2,3];Yao, Jun[4];Chen, Wen[1]

机构：[1]Shihezi Univ, Sch Pharm, Key Lab Xinjiang Phytomed Resources, Minist Educ, Shihezi 832000, Peoples R China;[2]Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China;[3]E China Univ Sci & Technol, Lab Biosyst & Microanal, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[4]Xinjiang Med Univ, Sch Pharm, Urumqi 830011, Xinjiang, Peoples R China

年份：2016

卷号：78

起止页码：308

外文期刊名：BIOSENSORS & BIOELECTRONICS

收录：;EI(收录号：20154801619916);WOS:【SCI-EXPANDED(收录号:WOS:000368954900044)】；

基金：The project financially supported by the Major Program for Science and Technology Development of Shihezi University (gxjs2014-zdgg04), National Natural Science Foundation of China (81260487, 81460543, 21575089), the Scientific Research Foundation for the Returned Overseas Chinese Scholars from Ministry of Human Resources and Social Security of China (RSLX201301), the Pairing Program of Shihezi University with Eminent Scholar in Elite University (SDJDZ201502), and Open Funding Project of the State Key Laboratory of Bioreactor Engineering.

语种：英文

外文关键词：Molecularly imprinted polymer; Nanoporous alloy microrod; Electrochemical sensor; Trace measurement; Dopamine

摘要：In this work, we developed a novel freestanding metallic microrod as working electrode for highly sensitive and selective electrochemical detection of trace dopamine (DA). The electrode was facilely fabricated via first dealloying smooth Au-Ag alloy microrod (AMR) into nanoporous Au-Ag alloy microrod (NPAMR) and further modifying with electro-polymerized molecularly imprinted polymer (MIP). Influencing factors during electro-polymerization process including pH value and molar ratio of monomer to template molecule were optimized. Under the optimal conditions, a linear range from 2 x 10(-13) to 2 x 10(-8) M for measuring DA was obtained with an ultralow detection limit of 7.63 x 10(-14) M (S/N=3). In addition, the MIP-modified electrode (MIP/NPAMR) was successfully employed to test DA in serum and brain samples. (C) 2015 Elsevier B.V. All rights reserved.