文献类型：期刊文献

英文题名：A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

作者：Chen, Mengjie[1];Huang, Chusen[1];He, Chunsheng[1];Zhu, Weiping[1];Xu, Yufang[1];Lu, Yunfeng[2]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA

年份：2012

卷号：48

期号：76

起止页码：9522

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000308088600024)】；

基金：The authors are grateful for the financial support from the National Natural Science Foundation of China (21076077), the National Science and Technology Pillar Program of China (2011BAE06B02), the National Basic Research Program of China (2010CB126100), the National High Technology Research and Development Program of China (2011AA10A207, 2012AA061601), the Fundamental Research Funds for the Central Universities and Shanghai Pujiang Program. W. Zhu is grateful for the support from Chinese Scholarship Council.

语种：英文

摘要：A glucose-responsive controlled-release system based on the competitive combination between glucose oxidase, glucosamine and glucose has been described, which exhibits perfect controlled release properties and high selectivity for glucose over other monosaccharides. This paved the way for a new generation of stimuli-responsive delivery systems.