文献类型：会议论文

英文题名：Research on Concanavalin A Crystallization in a Flow-Free Droplet-Based Device

作者：Du, Guan-ru[1];Zhang, Wen-jun[1,2];Ji, Ding-kun[3,4];Chen, Feng-juan[1];Yin, Di[1];Zhang, Hong-bo[1];Yin, Rui-xue[1];He, Xiao-peng[3,4];Yang, Shih-Mo[1]

机构：[1]East China Univ Sci & Technol, Complex & Intelligent Res Ctr, Sch Mech & Power Engn, Shanghai, Peoples R China;[2]Univ Saskatchewan, Dept Mech Engn, Saskatoon, SK, Canada;[3]East China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, Shanghai, Peoples R China;[4]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai, Peoples R China

会议论文集：2nd International Conference on Biomedical and Biological Engineering (BBE)

会议日期：MAY 26-28, 2017

会议地点：Guilin, PEOPLES R CHINA

语种：英文

外文关键词：Protein; Crystallization; Droplet-based

摘要：Protein crystallography is a very critical process that limits the development of pharmaceutical engineering. Microfluidic technology has provided an opportunity for protein crystallization. In this paper, a flow-free droplet-based device is presented for producing highly controlled crystals and fabrication of this device with polydimethylsiloxane (PDMS) is presented. The experiment was performed on the device and shows that the crystals of Con A and protein ligand (DK3) have a spherical structure.