文献类型：期刊文献

英文题名：Semicarbazide-based fluorescent probe for detection of Cu2+and formaldehyde in different channels

作者：He, Yuting[1];Wang, Hao[1];Fang, Xinhang[1];Zhang, Weibing[1];Zhang, Jingyuan[2];Qian, Junhong[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]Univ Alberta, Fac Sci, Dept Chem, Edmonton, AB T6G 2R3, Canada

年份：2023

卷号：299

外文期刊名：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

收录：;EI(收录号：20231914079305);WOS:【SCI-EXPANDED(收录号:WOS:001053096200001)】；

基金：This work was financially supported by National Key Research and Development Program (2022YFD1700801) .

语种：英文

外文关键词：Formaldehyde; Semicarbazide; Coumarin; Fluorescent discrimination; Cu2+

摘要：Two fluorescent sensors with the receptor semicarbazide respectively at 7- (CAA) and 3-position (CAB) of coumarin were designed and synthesized. CAA exhibits fluorescence turn-on response to Cu2+ by triggering the intramolecular charge transfer (ICT) process via Cu2+-catalyzed hydrolysis, and can detect formaldehyde (FA) at different channel by inhibiting the photo-induced electron transfer (PET). However, CAB displays quite different responses: the photophysical properties hardly changed in the presence of FA; while a three-stage fluorescence response of fast quenching, steady increasing and slowly decreasing was found upon addition of Cu2+. The high selectivity enabled CAA a good candidate for quantification of Cu2+ and formaldehyde as well as bioimaging Cu2+ in living cells. Good linear relationships between the fluorescence intensity and analyte concentration were observed in the range of 0.1-30 & mu;M for Cu2+ and 1.0-50 & mu;M for FA, and their detection limits (LOD) were calculated to be 0.43 & mu;M and 1.92 & mu;M (3 & delta;/k), respectively.